Yes, the beauty of affiliate marketing is that you can pick and choose which programs you want to promote and how many you choose to promote at a time. Often the best tactic to creating a sticky site that attracts and retains traffic is by promoting many complementary programs at once and offering valuable content to new customers on the benefits of either clicking, giving information and/or buying from the marketing partner. Whilst you can promote multiple programs, you should test out many programs when you start out, then settle on a few that match your needs and perform the best and work with them closely to optimize.